Pick's Disease Causes

What are the Causes of Pick's Disease?

People with Pick's disease develop abnormal protein called tau in their brain cells, similar to what occurs in Alzheimer's disease.^[1] Clumps of this protein are called Pick bodies.^[1] Why Pick's bodies occur is not known. Over time the front and side lobes of the brain shrink. Clinical evidence suggests that some cases of Pick's disease are inherited.^[6] Studies have linked frontotemporal dementia to a mutation in a gene on Chromosome 17.^[6]