Huntington's Disease Treatments

Treatments for Huntington Disease

There is currently no cure for Huntington's disease and there is no drug that stops or reverses the disease.^[3] However, it may be possible to control symptoms with the following medications and therapies, although physical and mental decline may eventually require long-term nursing home care.

Tetrabenazine may be taken to reduce the chorea, or jerky movements, that are a part of the disease.^[3] This drug can cause side effects such as trouble sleeping, sleepiness, nausea and restlessness. This drug is not recommended for depression treatment.

Tranquilizers and antipsychotics can control jerky movements and hallucinations.^[3[4]] These drugs may cause sleepiness and sometimes stiffness. Antidepressants may be useful to control depression and obsessive-compulsive behavior.^[3] Mood stabilizers such as lithium may be used as well.^[4]

Therapy to improve physical ability may be helpful.^[3] Speech therapy can improve the ability to talk and take part in conversations. Physical therapy can improve strength and flexibility. This can reduce the risk of falls. Occupational therapy can help with coping with memory and concentration problems. It may also help later on with eating, dressing and self-care.

Scientists are looking at ways to improve the course of the disease.^[3] They are studying certain cancer and AIDS drugs in relationship to Huntington's. They are also looking at the use of stem cells to repair brain cells. Recently, they begin testing of a new drug called ACR16 to improve muscle control and brain function.